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患有急性淋巴细胞白血病的儿童和青少年营养状况的改变
Izabela Kranjčec1, Ines Pranjić2, Jelena Roganović1
1Department of Oncology and Hematology, Children's Hospital Zagreb, 10000 Zagreb, Croatia.
Children (Basel, Switzerland)
|March 28, 2024
概括
接受化疗的儿童癌症患者经历了显著的体重增加和身高减少. 监测营养状况对于改善急性淋巴细胞白血病儿童的治疗结果至关重要.
科学领域:
- 儿科瘤学 儿科瘤学
- 临床营养学 临床营养学
- 血液学 血液学 血液学
背景情况:
- 营养不良是儿童癌症患者复发和生存的重要危险因素.
- 维持最佳营养状况对于有效的抗癌治疗结果至关重要.
- 急性淋巴细胞白血病 (ALL) 治疗可能会影响孩子的营养状况.
研究的目的:
- 为了评估化学疗法期间患有ALL的儿科患者营养状况的变化.
- 为了识别人体测量和血清白蛋白水平的变化.
- 了解营养状况与治疗结果之间的关系.
主要方法:
- 使用了人体测量 (体重,身高/长度,BMI) 的测量.
- 分析了血清白蛋白水平.
- 在诊断和强化治疗结束时评估了营养状况.
主要成果:
- 超重/肥胖率从诊断时的4.2%增加到治疗结束时的37.5%.
- 观察到体重和BMI因年龄而显著增加.
- 高度/长度的显著下降发生在年龄,特别是在高风险的ALL患者.
- 血清白蛋白水平没有显著的变化或与BMI相关.
结论:
- 对于儿科ALL的化疗可以导致显著的体重增加和减小生长速度.
- 密切的营养监测和支持对于儿科癌症患者至关重要.
- 需要进一步的研究来优化在ALL治疗期间的营养干预措施.
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