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Updated: Jun 29, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs

Published on: May 15, 2019

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主体和额外终端域抑制剂对突肉瘤细胞的治疗潜力

Yuki Kotani1, Yoshinori Imura1, Sho Nakai1

  • 1Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita 565-0871, Japan.

Cancers
|March 28, 2024
PubMed
概括

基基因和额外终端域 (BET) 抑制剂对突肉瘤 (SS) 是一种罕见的癌症有前途. 这些药物向SS18-SSX融合基因,诱导细胞死亡并提供新的治疗途径.

关键词:
这就是BCL2家族.域和额外终端域蛋白质抑制剂突性肉瘤 (Synovial Sarcoma) 是一个突性肉瘤.

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