探索椎 dystonia,震,以及他们的共存的头部方向感知
Aratrik Guha1,2, Hanieh Agharazi2, Palak Gupta1,2
1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA.
Brain sciences
|March 28, 2024
概括
患有宫 dystonia 或的人体验受损的前庭头部感知. 视觉方向感知在很大程度上不受影响,这表明在这些运动障碍中存在特定的小脑处理缺陷.
科学领域:
- 神经科学是一个神经科学.
- 运动障碍 运动障碍
- 感官感知是一种感官感知.
背景情况:
- 腹是第三个最常见的运动障碍,影响全球300万.
- 腹和震有共同的流行病学联系,非运动特征和平衡功能障碍.
- 小脑功能障碍是运动障碍和平衡问题的潜在潜在原因.
研究的目的:
- 为了研究孤立的宫 dystonia,孤立的震,以及它们的组合的头部感知.
- 为了比较视觉与前置领域的头部感知.
- 为了确定视觉定向感知是否优于前体定向感知.
主要方法:
- 利用了心理物理,特别是两个替代性的强制选择任务.
- 评估视觉和前体领域的自我运动方向的感知.
- 确定方向感知值,使用西格形心理测量功能.
主要成果:
- 与对照人群相比,在宫 dystonia (有或没有震) 和孤立的震中发现了升高的前庭头部感知值.
- 结合性 dystonia-tremor 和孤立的震时,静脉门值类似,但在孤立的宫性 dystonia 时更糟.
- 在所有测试条件下,视觉定向感知值的影响较小.
结论:
- 在运动障碍中存在线性翻译方向感知的共同和明显的缺陷.
- 研究结果表明,大脑小区负责前庭处理的区域参与了 dystonia 和震病理生理学.
- 在这些常见的运动障碍中区分感官处理变化.
相关概念视频
Major Somatic Sensory Pathways
951
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
951
Parkinson's Disease: Treatment
264
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
264
Equilibrium and Balance
4.7K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
4.7K
Indirect Motor Pathways
1.5K
The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
1.5K
Articulations of the Vertebral Column
1.9K
In addition to being held together by the intervertebral discs, adjacent vertebrae also articulate with each other at synovial joints formed between the superior and inferior articular processes called zygapophysial joints (facet joints). These are plane joints that provide for only limited motions between the vertebrae. The orientation of the articular processes at these joints varies in different regions of the vertebral column and serves to determine the types of motions available in each...
1.9K
Direct Motor Pathways
1.9K
The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
1.9K


