在成年人:管理和未解决的问题 - - 一个系统性审查下腔复发性神经质瘤
Lara Brunasso1, Chiara Avallone1, Ada Maria Florena2
1Neurosurgical Clinic, AOUP (Azienda Ospedaliera Universitaria Policlinico) "Paolo Giaccone", Post Graduate Residency Program in Neurologi Surgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, Via del Vespro 127, 90127 Palermo, Italy.
Brain sciences
|March 28, 2024
概括
在成年人中,下腔瘤很少见,通常发生在小脑或第四心室. 组织病理学可能无法预测瘤的行为,因此需要进一步研究以改善表征和治疗策略.
科学领域:
- 神经瘤学神经瘤学
- 神经外科 神经外科
- 病理学 病理学 病理学
背景情况:
- 结质瘤是一种罕见的中枢神经系统瘤,通常影响年轻人,位于叶.
- 成年人中的膜下瘤异常罕见,关于其临床表现和管理的数据有限.
- 这项研究重点关注未被报告的成年人体内关节瘤的发病率和特征.
研究的目的:
- 在成年患者中进行位于骨下部区域的结质瘤的系统审查.
- 分析人口统计数据,瘤特征,治疗方法和结果.
- 介绍一个说明性的案例,以补充系统审查的发现.
主要方法:
- 按照PRISMA指南进行了系统审查.
- 文献搜索产生了275篇文章,其中23篇最终被纳入分析.
- 提取的数据包括患者人口统计学,瘤位置和组织学,手术方法,辅助疗法和患者结局.
主要成果:
- 该综述包括27名患有下关节瘤的成年患者.
- 常见的位置包括小脑 (51%),第四心室 (40%),脑干 (11%) 和小脑角 (4%).
- 在44%的患者中进行了亚总切除 (STR),26%的患者进行了总总切除 (GTR),15%的患者进行了活检;22%的患者接受了辅助放射治疗. 在15%的患者,主要是高度瘤患者,在手术后1-12个月内观察到疾病复发.
结论:
- 在成年人群中,膜下腺瘤是一种罕见的实体.
- 目前的组织病理学分类可能无法完全预测这些瘤的临床行为.
- 进一步的研究是必不可少的,以提高对组织病理学特征的理解,并优化成年人体内膜腺瘤的治疗策略.
相关概念视频
Disorders of the Nervous Tissue
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Barrett Esophagus-II: Clinical Manifestations and Management
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Mitral Valve Prolapse II: Assessment and Management
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular tachycardia.
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aneurysm III: Interprofessional Care
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Aneurysm IV: Nursing Management
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...


