增长激素基因的单核酸多态性及其与黑孟加拉山羊生长特征的关系
Chollada Buranakarl1, Sumonwan Chamsuwan1, Sumpun Thammacharoen1
1Department of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Henri Dunant Rd., Pathumwan, Bangkok 10330, Thailand.
Animals : an open access journal from MDPI
|March 28, 2024
概括
生长激素 (GH) 基因中的单核酸多态 (SNP) 与黑孟加拉山羊的生长特征有关. A781G SNP与断奶前的生长有关,AA基因型表现优越.
科学领域:
- 动物遗传学动物遗传学
- 畜牧科学 畜牧科学 畜牧科学
- 分子生物学分子生物学
背景情况:
- 生长激素 (GH) 基因中的单核酸多态 (SNP) 是农场动物生长特征的潜在标记物.
- 了解遗传变异可以帮助提高牲畜生产率.
研究的目的:
- 在泰国黑孟加拉山羊中识别生长激素 (GH) 基因 (A781G和A1575G) 的单核酸多态 (SNP).
- 研究这些GH基因SNP与断奶前生长特征之间的关联.
主要方法:
- 77只黑孟加拉山羊在GH基因中对A781G和A1575GSNP进行基因定型.
- 测量断奶前生长特征,包括出生时和分娩后10周的体重,身高,长度和胸围.
- 计算不同断奶前期的平均每日增益 (ADG).
- 对不同基因型的生长特征进行比较,考虑到母的 litter 尺寸.
主要成果:
- 在A1575G SNP中,只显示了CC基因型. 在A781G SNP有三个基因型:AA,AB和BB.
- 与AB和BB基因型相比,A781G的AA基因型的山羊的10周体重 (W10) 和10周长度 (L10) 显著更高.
- 与BB基因型相比,AA基因型在4-8周之间 (ADG4-8W) 的平均每日增益也显着更高.
结论:
- 在生长激素基因中的A781G SNP与黑孟加拉山羊的断奶前生长特征有显著的关联.
- 对A781G SNP的AA基因型在断奶前期表现出优异的生长性能,表明其作为增长改善的遗传标记物的潜力.
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