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食氧醇补充剂对LPS挑战型肉的生长性能,肠道形态和氧化和炎症状态的影响

Kelly M M Dias¹, Carlos H Oliveira¹, Arele A Calderano¹

¹Department of Animal Science, Federal University of Viçosa, Viçosa 36570-900, Minas Gerais, Brazil.

Animals : an open access journal from MDPI

|March 28, 2024

概括

氧醇 (HT) 补充剂改善了受脂多糖化物 (LPS) 挑战的鸟类的肉生长性能和肠道健康. HT减轻了肠道损伤,调节了抗氧化剂和免疫反应,表明其作为有益的料添加剂的潜力.

科学领域:

禽畜科学禽畜科学禽畜科学
动物营养动物营养
免疫学免疫学免疫学

背景情况:

脂聚糖 (LPS) 挑战对 brojler 的生长和肠道完整性产生负面影响.
氧醇 (HT) 是一种多,具有抗氧化和抗炎性质.
了解HT对LPS挑战型肉的影响对于改善家禽生产至关重要.

研究的目的:

为了评估氧醇 (HT) 对生长性能,肠道形态和抗氧化剂/免疫反应的影响,在受脂多糖化物 (LPS) 挑战的 brojlers.

主要方法:

180只Cobb500TM雄性肉被分为对照,LPS挑战和LPS + HT (10毫克/kg料) 组.
在14日,16日,18日和20日,LPS被输入腹腔内.
分析了生长参数,器官重量,骨形态 (骨高度,密室深度) 和基因表达 (NF-κB,CAT,GPx,SOD,IL-10,IL-1β,IL-8).

主要成果:

补充HT显著改善了体重 (BW),体重增加 (BWG) 和料转换率 (FCR).
HT降低了骨密室深度 (CD),并增加了骨高度与密室深度的比率 (VH:CD).
在HT下调的mRNA表达的催化酶 (CAT),谷氨过氧化酶 (GPx),介质素-10 (IL-10) 和介质素-1β (IL-1β).

结论:

氧醇可以提高 brojler 的生长性能,并减轻 LPS 引起的 jejunal 粘膜损伤.
在受挑战的肉中,HT调节了抗氧化酶活性和炎症性细胞因子表达.
作为一种料添加剂,HT有望改善肉的健康状况和在炎症条件下的性能.

关键词:

抗氧化剂是一种抗氧化剂.用于料添加剂的料添加剂基因表达的基因表达方式简 (Jejunum) 是一个脂多糖类糖化物 (Lipopolysaccharide) 是一种脂多糖类糖.

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