临床和流行病学评估在亚马逊前地区住院治疗SARS-CoV-2的儿童和青少年
Marilene Ribeiro1,2, Luis Sousa3,4, Johnatha Oliveira5
1Postgraduate Program in Management of Health Programs and Services, Campus Renascença, CEUMA University, São Luís 65075-120, Brazil.
Biomedicines
|March 28, 2024
概括
儿童的COVID-19通常是温和的,但儿科多系统炎症综合征 (PMIS) 具有严重的风险. 快速诊断对于指导治疗和避免在儿科呼吸道感染中不必要使用抗生素至关重要.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 儿童和青少年的COVID-19经常模仿其他呼吸道病毒感染.
- 儿童COVID-19病例,特别是肺炎,在现有文献中代表性不足.
- 与成年人相比,儿童和青少年的感染率通常较低,疾病较轻.
研究的目的:
- 调查SARS-CoV-2患者住院儿科患者的临床和流行病学特征.
- 分析巴西特定地区儿童和青少年的COVID-19结果.
主要方法:
- 从2020年3月到2021年3月的医疗记录的回顾性分析.
- 纳入标准:年龄在0-13岁的患者,社区获得的肺炎诊断.
- 这项研究是在巴西圣路易斯的四家公立医院进行的.
主要成果:
- 最受影响的年龄组是1-5岁 (约. 40%). 在这个问题上.
- 在78.6%的儿科COVID-19病例中存在发烧;慢性神经疾病是最常见的并发症.
- 在24.8%的病例中观察到地面玻璃的不透明性;17名患者被诊断为儿科多系统炎症综合征 (PMIS),18名患者死亡.
结论:
- 虽然SARS-CoV-2感染在儿童群体中通常是轻微的,但PMIS病例是严重的,可能致命的.
- 炎症生物标志物增加与儿童的严重COVID-19和PMIS有关.
- 这项研究强调了需要准确的诊断来优化治疗决策,减少不分青红白的抗生素使用.
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