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Updated: Jun 29, 2025

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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作为双核受体4A1 (NR4A1) 和NR4A2连接体的双醇衍生物

Srijana Upadhyay1, Amanuel Esayas Hailemariam1, Fuada Mariyam1

  • 1Department of Veterinary Physiology, Texas A&M University, College Station, TX 77843, USA.

Biomolecules
|March 28, 2024
PubMed
概括

双醇化合物 (DIM-3,5和DIM8-3,5) 是NR4A1和NR4A2受体的双联体. 这些强大的瘤生长抑制剂在质母细胞瘤和结肠癌细胞中表现出细胞毒性.

关键词:
在NR4A1中,在NR4A2中,双内 (bis-indole) 是一种双内.双重结合的双重结合

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