传染性内心炎由Capnocytophaga的物种-A叙述审查
Despoina Spentzouri1, Stella Baliou2, Petros Ioannou2
1Internal Medicine, University Hospital of Heraklion, 71110 Heraklion, Greece.
Medicina (Kaunas, Lithuania)
|March 28, 2024
概括
经常来自动物咬伤的Capnocytophaga细菌可以导致严重的传染性内心炎 (IE). 本综述强调了Capnocytophaga IE的关键特征,治疗方法和结果,并指出死亡率为16.1%.
科学领域:
- 微生物学与传染病的研究
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 卡普诺细胞菌是人类和动物口腔菌群中发现的格拉姆阴性细菌.
- 这些细菌可以引起严重的感染,包括传染性内心炎 (IE),特别是在动物咬后.
- 现有的关于与Capnocytophaga相关的IE的文献需要进行全面的审查.
研究的目的:
- 对所有报告的人类感染性内心炎病例进行叙述性审查,由Capnocytophaga物种引起.
- 整合有关Capnocytophaga IE.流行病学,微生物学,临床表现,治疗和结果的信息.
主要方法:
- 使用PubMed,Cochrane图书馆和Scopus数据库进行了系统的文献搜索.
- 到2023年9月11日发表的研究,详细介绍了由Capnocytophaga spp.引起的人类IE病例. 被包括在内.
- 分析了31项符合条件的研究,涉及31名患者的数据.
主要成果:
- 在38.5%的患者中报告了狗咬伤;9.7%的患者有假体门.
- 大动脉和三管门最常受到影响.
- 常见的表现包括发烧,栓塞现象,副腹,败血症;死亡率为16.1%.
结论:
- 细胞菌物种是传染性内心炎的重要原因,通常与动物接触有关.
- 及时诊断和适当的抗微生物治疗 (β-乳糖胺,氨基糖胺) 与外科手术相结合至关重要.
- 尽管接受治疗,但Capnocytophaga IE具有显著的死亡风险,强调需要提高认识和及时管理.
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