在接受全甲状腺切除术的患者中,甲状腺微瘤的发生频率与良性指示-五年后期回顾
Vasiliki Magra1, Kassiani Boulogeorgou2, Eleni Paschou1
1Third Department of General Surgery, Medical School, AHEPA University Hospital, Aristotle University of Thessaloniki, 54621 Thessaloniki, Greece.
Medicina (Kaunas, Lithuania)
|March 28, 2024
概括
在甲状腺切除术后经常偶然发现患有良性疾病的乳头小瘤,影响7.67%的患者. 这凸显了在患有良性甲状腺疾病的患者中考虑潜在的乳头甲状腺微癌的必要性.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 偶然的甲状腺癌 (ITCs),特别是乳头小瘤 (PTMCs),是常见的,并且经常在甲状腺切除术后被检测出来.
- 乳头甲状腺微瘤被定义为小于10毫米的乳头甲状腺瘤.
- 这些在临床上是隐秘的,并且经常在组织病理学报告中偶然发现.
研究的目的:
- 为了确定乳头甲状腺微瘤 (PTMCs) 的发病率,在接受甲状腺切除术的患者中,因为怀疑是良性甲状腺疾病.
主要方法:
- 一项回顾性对431名在2016年至2021年期间接受甲状腺切除为良性征兆的患者的组织病理学报告的回顾性审查.
- 排除在手术前已知或疑似恶性瘤的患者.
主要成果:
- 在最初为良性甲状腺疾病进行手术的患者中,7.67% (33/431) 发现了乳头甲状腺微瘤 (PTMC).
- 偶然的恶性病变,包括PTMC,在8.35%的研究队列中被发现.
- PTMCs通常是多焦点的 (24/33) 并且经常与多节 (64%) 或哈希莫托甲状腺炎 (36%) 相关.
结论:
- 乳头小瘤是针对良性疾病进行的甲状腺切除术中的重要偶然发现.
- 这种高发病率表明,在治疗良性,特别是结节性甲状腺疾病的患者时,应该考虑PTMC.
- 对于良性甲状腺疾病患者来说,全甲状腺切除术可能是值得考虑的,因为有可能偶尔检测到PTMC.
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