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心房节奏负面影响左心房的形态和功能参数类似于心房心室失调

Mindaugas Viezelis¹, Gintare Neverauskaite-Piliponiene², Agne Marcinkeviciene¹

¹Department of Cardiology, Lithuanian University of Health Sciences, A. Mickeviciaus Str. 7, LT-44307 Kaunas, Lithuania.

Medicina (Kaunas, Lithuania)

|March 28, 2024

概括

高心房节奏,即使没有心房失调,也会在心脏起器植入后对左心房 (LA) 功能和结构产生负面影响. 这些对LA功能的有害影响很早就显现出来,并随着时间的推移而持续.

科学领域:

心脏病学心脏病学
生物医学工程生物医学工程
医疗器械医疗器械

背景情况:

心房 (AV) 不同步和节拍器节拍影响左心房 (LA) 功能.
双腔心脏起器植入可以导致LA的形态和功能变化.

研究的目的:

评估心房和心室节拍对LA在双腔心脏起器植入后的形态和功能变化的影响.
在患有鼻结病 (SND) 或心房阻塞 (AVB) 的患者中研究节奏负担和LA功能之间的关系.

主要方法:

预计将121名带有双腔起器的受试者纳入研究.
受试者根据指示 (SND/AVB) 和节奏设置 (例如,DDR 60,DDD 60,DDD 40) 进行分组.
在植入后的1个月和3个月,使用心声回声,测量体积参数和应变来评估LA功能.

主要成果:

一个高心房 (A) 节奏负荷与低心室 (V) 节奏 (高A,低V) 三个月后显著降低了LA水库和收缩性应变.
在低A,高V组中,重新建立的AV同步维持了LA储应变.
高A,高V组显示了下降LA水库应变的趋势,尽管在统计学上并不显著.

结论:

高心房节拍负担,独立于AV失调和心室节拍,损害LA功能和形态.
这些对LA参数的负面影响发生在心脏起器植入后不久,并且持续.
心脏起器编程策略应考虑高心房节奏对左心房功能的潜在影响.

关键词:

心脏节奏节奏是指心脏节奏节奏.左心房的功能是左心房功能.压力压力压力压力

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