在多民族队列研究中的甲状腺癌生存率
Janine V Abe1, Song-Yi Park1, Christopher A Haiman2
1Cancer Epidemiology Program, University of Hawai'i Cancer Center, Honolulu, HI 96813, USA.
概括
甲状腺癌 (TC) 的生存率因性别和种族而异. 男人和菲律宾患者面临更高的死亡风险,突出了TC结果的差异.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 甲状腺癌 (TC) 在美国的5年生存率很高 (>95%).
- 调查性别和种族/种族的生存差异对于了解不同人群中TC结果至关重要.
研究的目的:
- 为了检查基于性别和种族/种族的甲状腺癌 (TC) 存活率差异,在多民族的美国队列中.
- 为了比较TC病例和没有甲状腺癌的对照组之间的死亡风险.
主要方法:
- 利用了来自多民族队列 (MEC) 研究的数据,确定了605例TC病例.
- 采用考克斯模型来分析全因死亡率,调整临床和人口因素.
- 比较TC病例的生存率与匹配的MEC对照.
主要成果:
- 女性TC病例的整体5年生存率为84.4%,男性为68.7% (p < 0.0001).
- 与日裔美国人相比,非洲裔美国人,夏威夷原住民和菲律宾人TC病例的生存率较低.
- 与对照组相比,男性和菲律宾TC病例的死亡风险增加.
结论:
- 在TC生存率方面的性别和种族/种族差异反映了一般人群中的差异.
- 患有TC的男性和菲律宾血统人士的死亡风险较高.
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