在COVID-19患者中嗅觉功能障碍的预后价值:COVIDORA研究
Anne-Laure Hamel1, Léo Delbos2,3, Pierre-André Natella1
1URC, Hôpital Henri Mondor, Assistance Publique des Hôpitaux de Paris, F-94010 Créteil, France.
Life (Basel, Switzerland)
|March 28, 2024
概括
在COVID-19患者的嗅觉功能障碍 (OD) 预测,在大流行的第一波期间,住院的风险较低. 这表明OD可能表明疾病进展较轻,并减少了对重症监护的需求.
科学领域:
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 流行病学 流行病学
背景情况:
- 有限的研究将嗅觉功能障碍 (OD) 与COVID-19严重程度相关联.
- 评估OD作为疾病管理的预测因素至关重要.
研究的目的:
- 为了确定嗅觉功能障碍是否预测COVID-19的严重程度.
- 分析OD和患者管理 (门诊,医院,ICU) 之间的关联.
主要方法:
- 在481名COVID-19患者的前性多中心队列研究中.
- 在症状出现后10天内进行随访耳鼻科医生咨询.
- 评估了从诊断到临床过程中的医疗管理演变.
主要成果:
- 奥迪的患病率为60.7%,主要在65岁以下的女性中,并发症较少.
- 99.3%的OD患者患有非严重的COVID-19.
- 与门诊患者相比,OD患者的住院住院 (标准或ICU) 显著减少.
结论:
- 嗅觉功能障碍可能成为降低住院风险的预测因素.
- 在最初的疫情浪潮中,OD可能表明COVID-19的临床过程较温和.
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