在COVID-19后持续的嗅觉和味觉功能障碍
Malgorzata Buksinska1, Piotr Henryk Skarzynski2,3,4, Danuta Raj-Koziak5
1Otorhinolaryngosurgery Clinic, World Hearing Center, Institute of Physiology and Pathology of Hearing, 05-830 Kajetany, Poland.
Life (Basel, Switzerland)
|March 28, 2024
概括
后COVID-19嗅觉功能障碍 (OD) 是常见的,大多数病例出现在外围. 需要进行研究,因为对嗅觉和味觉丧失的有效治疗方法仍然有限.
科学领域:
- 神经学 神经学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
背景情况:
- 嗅觉和味觉的突然丧失是COVID-19的已知的症状.
- 后COVID-19嗅觉功能障碍 (OD) 和味觉 (味觉) 功能障碍 (GD) 显著影响生活质量.
- 了解这些功能障碍的严重程度和特征对于患者管理至关重要.
研究的目的:
- 为了评估COVID-19后嗅觉功能障碍 (OD) 的严重程度.
- 评估OD和味觉 (味觉) 功能障碍 (GD) 之间的关系.
- 为了调查后COVID-19 OD的潜在中心或外围性质.
主要方法:
- 报名的81名受试者在COVID-19后患有主观OD.
- 嗅觉功能障碍 (OD) 使用嗅探棒测试 (SST) 进行评估.
- 用味道带测试 (TS) 评估味道功能障碍 (GD).
主要成果:
- 无氧化 (22%) 和低氧化 (64%) 是普遍存在的;14%观察到正常化.
- 幻觉 (虚构的气味) 发生在36%的患者中,但与嗅觉敏感性无关.
- 味觉功能障碍很常见,甜味最容易辨认,味最难辨认. OD和GD之间的相关性很弱,并且没有统计学意义.
结论:
- 在COVID-19后的嗅觉功能障碍似乎主要是外围的.
- 评估OD的严重程度对于临床治疗策略很重要.
- 由于缺乏完全有效的治疗方法,对COVID-19后的OD进行进一步研究是必要的.
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