肺外因素与早期成年期肺功能减弱之间的关系中的性别差异
Keiko Doi1,2, Tsunahiko Hirano1, Keiji Oishi1
1Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-kogushi, Ube, Yamaguchi 755-8505, Japan.
性别特定的因素,如男性的左手握力和女性的骨矿物质含量,可能有助于选年轻人的肺功能减弱,表明潜在的呼吸系统问题.
科学领域:
- 肺病学和呼吸系统医学
- 体育医学和生理学运动医学和生理学
- 生物识别和身体组成分析分析.
背景情况:
- 成年早期肺功能下降与未来的健康风险有关,性别特异性关联需要进一步探索.
- 调查肺外变量作为年轻成年人呼吸功能障碍的潜在查标志物至关重要.
研究的目的:
- 检查年轻成年人肺功能和肺外变量之间的性别特异关系.
- 评估手握强度和骨矿物质含量作为呼吸功能障碍查标记物的有用性.
主要方法:
- 151名医学学生提供了临床数据,手握强度 (HS),身体组成 (SMI,WBPhA,BMC) 和肺功能 (VC,FVC,FEV1) 测量.
- 进行了统计分析,以确定肺功能和肺外变量之间的相关性,按性别分层.
主要成果:
- 在所有参与者中,一秒钟内强迫呼气量 (FEV1) 与BMI,SMI,WBPhA,BMC和HS有显著的相关性.
- 性别特定的分析显示,FEV1与男性的左HS和女性的BMC有着最强的正相关性.
- 左HS和BMC表现出很好的预测价值,用于识别FEV1的最低四分位数中的个体,具有高灵敏度.
结论:
- 确定了肺内和肺外因子之间的性别特异性关联,特别是男性的左HS和女性的BMC.
- 这些因素有望成为在成年早期查疑似呼吸功能障碍的有价值工具.
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