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Updated: Jun 29, 2025

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阿司匹林通过FXR和ET-1信号通路引起肠道损伤

Qiuxia Lin1,2, Binbin Zhang1,2, Manyun Dai2

  • 1Laboratory of Hepatointestinal Diseases and Metabolism, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China.

International journal of molecular sciences
|March 28, 2024
PubMed
概括

长期使用阿司匹林会通过改变胆酸和激活内甲蛋白-1 (ET-1) 来引起胃肠道损伤. 激活Farnesoid X受体 (FXR) 和抑制ET-1可以缓解这些损伤.

关键词:
在 FXR 和 FXR 之间.阿司匹林是一种阿司匹林.胆酸胆酸是一种胆酸.末端蛋白 1 1 的情况.肠道损伤是指肠道损伤.

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