在INCLD健康队列中,习惯性聚醇消费和肠道微生物群之间的关系
Alexandra Adorno Vita1,2, Kristen M Roberts3, Anders Gundersen1
1Helfgott Research Institute, National University of Natural Medicine, Portland, OR 97201, USA.
Nutrients
|March 28, 2024
概括
饮食中的多,包括草药和香料,影响肠道细菌. 摄入较高的多可能会减少机会性病原体,促进成年人更健康的肠道微生物群.
科学领域:
- 微生物学 微生物学
- 营养科学 营养科学
- 人类健康 人类健康 人类健康
背景情况:
- 多与肠道健康有关,但它们来自习惯饮食 (包括草药和香料) 的影响需要进一步研究.
- 了解多-肠道微生物群相互作用对于饮食建议至关重要.
研究的目的:
- 调查健康成年人习惯性聚醇消费与肠道微生物群组成之间的关系.
- 确定与饮食中摄入多和草药/香料使用相关的特定微生物种群.
主要方法:
- 对国际生活方式决定健康因素队列 (INCLD健康) 队列 (n=96) 的分析.
- 利用饮食问卷和16S rRNA基因测序进行肠道微生物组分析.
- 检查了多摄入量 (每天毫克) 和草药/香料使用频率与微生物种类和多样性之间的关联.
主要成果:
- 微生物种类,而不是多样性,根据多的消费水平有显著差异.
- 鉴定了多摄入量的探索性生物标志物:乳杆菌,细菌,菌,欧细菌腹腔组,Ruminococcus扭矩组和Sutterella.
- 已确定用于草药/香料使用的探索性生物标志物:Lachnospiraceae UCG-001,Lachnospiraceae UCG-004,Metanobrevibacter,Lachnoclostridium和Lachnotalea. 这些生物标志物包括:
- 发现了多醇消费和具有促炎潜力的种群之间的反向关系.
结论:
- 习惯性摄入多,包括从草和香料中摄入的多,与特定的肠道微生物特征有关.
- 更高的聚醇摄入量可能会促进肠道环境,机会性和潜在的促炎细菌的相对丰度较低.
- 研究结果表明,饮食中的多在调节肠道微生物群以减少毒性方面可能发挥作用.
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