治疗胃肠道疾病的益生菌和益生菌
Sameeha Rau1, Andrew Gregg1, Shelby Yaceczko1
1Vatche & Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90095, USA.
Nutrients
|March 28, 2024
概括
本综述探讨了益生菌和益生菌如何影响胃肠道 (GI) 疾病的肠道微生物群. 证据强调了这些补充剂对菌株特定的益处和潜在的不良影响.
科学领域:
- 微生物学 微生物学
- 胃肠病学 胃肠病学
- 营养科学 营养科学
背景情况:
- 肠道微生物在胃肠道 (GI) 疾病中的作用是一个关键的研究领域.
- 饮食显著影响肠道微生物组的组成和功能.
- 益生菌和益生菌显示出通过调节微生物群来管理胃肠道疾病的潜力.
研究的目的:
- 审查有关各种胃肠道疾病的益生菌和益生菌现有证据.
- 突出这些干预措施的菌株特异性影响.
- 为了确定与其使用相关的任何已知的不良影响.
主要方法:
- 对胃肠道疾病中益生菌和益生菌研究的系统文献综述.
- 分析证据,重点关注特定的微生物菌株,剂量和治疗持续时间.
- 检查报告的安全数据和不良事件.
主要成果:
- 关于菌株,剂量和治疗持续时间的研究存在显著的异质性.
- 益生菌和益生菌显示出潜在的益处,但效果往往取决于菌株.
- 安全问题,特别是与活生物体有关的安全问题,需要仔细考虑.
结论:
- 菌株特异性影响对于了解肠道疾病中的益生菌和益生菌疗效至关重要.
- 需要进行进一步的研究,以制定明确的,基于证据的使用建议.
- 仔细考虑安全性和菌株特异性对于临床应用至关重要.
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