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Updated: Apr 15, 2026

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通过基于结构的虚拟查和分子动力学模拟,发现了新型非共价KRAS G12D抑制剂

Zhenya Du1,2, Gao Tu1, Yaguo Gong1

  • 1State Key Laboratory of Quality Research in Chinese Medicine, Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, Macau Institute for Applied Research in Medicine and Health, Faculty of Chinese Medicine, Macau University of Science and Technology, Macao 999078, China.

Molecules (Basel, Switzerland)
|March 28, 2024
PubMed
概括

研究人员使用计算方法确定了KRAS G12D突变的新型非共价抑制剂. 这些有前途的候选药物为向癌症治疗提供了新的途径.

关键词:
在KRASG12D中使用.分子动力学分子动力学非共价抑制剂的非共价抑制剂虚拟选 虚拟选 虚拟选

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