相关实验视频

Updated: Jun 29, 2025

Probiotic Studies in Neonatal Mice Using Gavage

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

神经发育的第一千天内肠道微生物组:从微生物组的角度进行系统审查

Nathalia F Naspolini¹, Paulo A Schüroff¹, Maria J Figueiredo²

¹School of Arts, Sciences and Humanity, University of São Paulo, São Paulo 03828-000, Brazil.

|March 28, 2024

概括

婴儿的肠道微生物群影响大脑发育和神经发育结果. 像Bacteroides和Bifidobacterium这样的关键细菌与健康的大脑功能有关,但需要对具体机制进行更多研究.

科学领域:

微生物学微生物学
神经科学是一个神经科学.
发展生物学发展生物学

背景情况:

生命早期的肠道微生物群对大脑发育至关重要.
它还在精神和神经退行性疾病中发挥作用.

研究的目的:

在婴儿的头一千天内,系统地审查肠道微生物组评估.
调查影响大脑发育和神经发育结果的关键微生物组参与者和机制.

主要方法:

对婴儿肠道微生物组和神经发育结果的研究进行系统审查.
分析特定细菌属和神经发育指标之间的关联.

主要成果:

细菌菌和双菌与认知,运动和行为发育以及神经类型大脑发育有关.
拉克诺斯皮拉菌 (Lachnospiraceae),细菌菌 (Streptococcus) 和便细菌 (Faecalibacterium) 显示对发育有不同的影响.
关于代谢途径和微生物基因的有限的机械洞察力被发现.

结论:

肠道微生物组显著影响早期大脑发育.
需要进一步的研究来将特定的肠道细菌与功能途径联系起来,以便全面了解微生物组-肠道-大脑轴.

关键词:

细菌菌菌类的存在这种细菌是Bifidobacterium.生命早期的微生物组微生物机制的微生物机制微生物群肠大脑轴神经发育的结果.

更多相关视频

High-Throughput Screening of Microbial Isolates with Impact on Caenorhabditis elegans Health

High-Throughput Screening of Microbial Isolates with Impact on Caenorhabditis elegans Health

Published on: April 28, 2022

Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice

Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice

Published on: June 2, 2022

相关概念视频

Anatomy of the Intestines

Anatomy of the Intestines

Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...