探索特定益生菌菌株对口腔病原体的体外抗菌潜力
Diletta F Squarzanti1, Federica Dell'Atti2, Alessandro C Scalia3
1Synbalance Srl, 21040 Origgio, VA, Italy.
Microorganisms
|March 28, 2024
概括
某些益生菌菌株有效地抑制口腔病原体,如Streptococcus mutans和Aggregatibacter actinomycetemcomitans. 这两种病原体的作用非常明显. 这些发现表明益生菌可以帮助恢复口腔平衡并改善整体健康.
科学领域:
- 微生物学 微生物学
- 口腔健康 口腔健康
- 益生菌 益生菌是一种益生菌.
背景情况:
- 口腔微生物群不平衡与口腔疾病和全身健康问题有关.
- 益生菌干预显示出恢复口腔微生物平衡的潜力.
研究的目的:
- 选可行的益生菌菌株,以检测它们对口腔病原体的抗菌和抗粘活性.
- 评估选择益生菌在预防病原体生长和粘附方面的有效性.
主要方法:
- 对十种益生菌菌株进行查,以对抗Streptococcus mutans和Aggregatibacter actinomycetemcomitans.
- 用阿加尔覆盖,板数和扫描电子显微镜来评估抑制和粘附.
- 使用预防和治疗模型来评估益生菌的疗效.
主要成果:
- 七种益生菌菌株显示出针对口腔病原体的显著抑制区.
- 乳种植物菌植物 PBS067,乳种植物菌 rhamnosus LRH020和三个L. paracasei菌株 (LPC 1101,LPC 1082,LPC 1114) 显示出显著的病原体生长和粘附抑制.
- 观察到抑制是以特定菌株的方式进行的 (p < 0.0001).
结论:
- 特定的益生菌菌株,包括L. plantarum PBS067和L. rhamnosus LRH020,对关键的口腔病原体有效.
- 这些益生菌可以作为改善口腔和全身健康的辅助剂.
- 个性化的益生菌治疗对未来的口腔健康管理具有前途.
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