在下重建后,使用特定的主体肌肉骨建模预测下开口功能
Junpeng Chen1,2, Jing Wang1, Jianqiao Guo3
1Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology, Beijing, China.
Journal of oral rehabilitation
|March 28, 2024
概括
这项研究验证了一种特定于个体的肌肉骨模型,用于预测下重建后的下运动. 该模型准确地预测了近距离的开,有助于手术规划和三风险评估.
科学领域:
- 生物力学 生物力学
- 手术规划 手术规划
- 计算建模 计算建模
背景情况:
- 部重建往往导致异常的部运动.
- 在体肌肉骨模型可以预测术后下下肢动力学.
- 验证这些模型和理解准确性因素至关重要.
研究的目的:
- 使用对象特定的肌肉骨模型,研究下开关运动和下后重建.
- 分析影响这些预测准确性的因素.
主要方法:
- 为10名患者建立了特定的下肌肉骨模型.
- 使用圆束计算机断层扫描,下运动和EMG数据.
- 根据手术后6个月的测量验证的预测.
主要成果:
- 该模型在下切肢位移方面实现了31.4%的RMSE,而在峰开口方面则实现了4.9毫米的误差.
- 预测准确度受到患者年龄,术后感染和放射治疗的影响.
- 马塞特肌肉脱落与大开口的相关性很小.
结论:
- 下肌肉骨模型成功预测了短距离的下开放后重建.
- 这为手术规划提供了一种新的方法,可以预测三风险.
相关概念视频
Bone Remodeling
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Bone Remodeling and Repair
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...


