第三类PI3K激酶Vps34的双重活性对NK细胞发育和衰老至关重要

Shasha Chen1,2,3,4, Zehua Li5, Jin Feng5

  • 1Department of Allergy, The First Affiliated Hospital of Anhui Medical University and Institute of Clinical Immunology, Anhui Medical University, Hefei, 230032, China.

概括

酸3-酶Vps34对于自然杀手 (NK) 细胞的发育和功能至关重要. 它的缺失会损害NK细胞数量和IL-15信号传递,同时也加速NK细胞衰老.

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