体重指数定义的肥胖与腹腔大动脉化相关的年龄差异
Tangmeng Guo1,2, Lili Huang3, Zhijian Luo4
1Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Frontiers in endocrinology
|March 28, 2024
概括
在52岁以上的成年人中,肥胖与腹腔大动脉化 (AAC) 的风险降低有关. 这一发现表明,年龄较大可能解释心血管疾病中的肥胖悖论.
科学领域:
- 心血管疾病研究研究
- 肥胖研究 肥胖研究
- 老年医学 老年医学
背景情况:
- 以前的研究将年轻的年龄与心血管疾病中的肥胖悖论联系在一起.
- 这项研究探讨了关于肥胖悖论的另一种观点.
- 意想不到的发现挑战了现有的假设.
研究的目的:
- 为了检查美国人口中肥胖和腹腔大动脉化 (AAC) 之间的关系.
- 确定年龄是否影响肥胖和AAC之间的关联.
- 提供对肥胖悖论的新见解.
主要方法:
- 对2013-2014年NHANES数据进行横截面分析.
- 包括947名符合特定标准的参与者.
- 使用平滑曲线拟合和多变量回归分析,对共变量进行调整.
主要成果:
- 在52岁及以上的个体中,肥胖与AAC的风险较低有关.
- 在老年人中,肥胖组的AAC得分下降了 (0.92-1.11分).
- 特定特征 (男性,低LDL,DM,吸烟等) 在52岁以上的肥胖个体中,与较低的AAC风险进一步相关.
结论:
- 在52岁以上的美国成年人中,肥胖与腹腔大动脉化风险降低相关.
- 高龄化成为潜在的因素,导致心血管健康中的肥胖悖论.
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