改善生活的基本8有助于减缓生物衰老过程:基于NHANES 2007-2010数据的横截面研究
Dongzhe Wu1, Chaoyi Qu2, Peng Huang1
1Exercise Biological Center, China Institute of Sport Science, Beijing, China.
Frontiers in public health
|March 28, 2024
概括
生活必需品8 (LE8) 的较高分数与较慢的生物衰老有关,由较低的表型年龄加速 (PhenoAgeAccel) 表示. 保持健康的生活方式对于健康的衰老至关重要.
科学领域:
- 老年学与公共卫生
- 心血管健康和生活方式医学 心血管健康和生活方式医学
背景情况:
- 生活必需品8 (LE8) 是对心血管健康的综合测量.
- 现型年龄加速 (PhenoAgeAccel) 反映了与时间年龄相对的生物衰老.
研究的目的:
- 在美国成年人中检查LE8和PhenoAgeAccel之间的关联.
- 评估LE8对生物衰老的影响,以获得公共卫生见解.
主要方法:
- 从NHANES (2007-2010) 中对7339名美国成年人的横截面分析.
- 用于分析LE8和PhenoAgeAccel的加权通用线性回归和受限立方线.
- 根据性别和相互作用效应进行了子组分析.
主要成果:
- 在所有模型中,较高的LE8分数与较低的PhenoAgeAccel显著相关.
- 这种反向关系在男性和女性参与者中是一致的.
- 体重指数和糖尿病状况显示了相互作用效应,影响了LE8-PhenoAgeAccel关系.
结论:
- 根据LE8的测量,更健康的生活方式与生物衰老的减缓有关.
- 调查结果支持公共卫生倡议,促进健康的生活方式以缓解衰老.
- 需要进一步的研究来探索因果关系和跨文化普遍性.
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