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Updated: Jun 29, 2025

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TIGIT调节了CD4+ T细胞对多微生物败血症的免疫力

Xuexin Zhong1, Haiping Xie1, Shuang Wang1

  • 1Department of Rheumatology and Clinical Immunology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Frontiers in immunology
|March 28, 2024
PubMed
概括

这项研究表明,免疫检查点T细胞免疫球蛋白和ITIM域 (TIGIT) 在败血症中起着至关重要的作用. 抑制TIGIT增强了免疫反应,并减少了小鼠的败血症严重程度,这表明TIGIT是潜在的治疗标.

关键词:
在CD4+T细胞中.这是一个紧张的紧张.对抗细菌反应的反应.这就是CLP.已经有了血症.

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