对Crossobamon orientalis体油的化学组成和抗菌研究
Shakeel Ahmad1, Kashif Ali2, Khalil Ahmad3
1Institute of Zoology, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Heliyon
|March 28, 2024
概括
沙漠黑 (Crossobamon orientalis) (COO) 的油显示出显著的抗氧化和抗菌特性. 这种天然的油提取物显示出开发抗病毒和细菌感染的新治疗剂的潜力.
科学领域:
- 药理学和传统医学的医学.
- 动物学和生物化学 动物学和生物化学
背景情况:
- 壁产品被用于亚洲传统医学,但沙漠物种如Crossobamon orientalis的药用潜力在很大程度上没有得到研究.
- 来自动物来源的天然生物活性化合物的探索提供了新的治疗途径.
研究的目的:
- 评估从Crossobamon orientalis (COO) 提取的油的化学成分和生物活性.
- 评估COO提取物的抗氧化,抗病毒和抗菌潜力,用于医学应用.
主要方法:
- 气色谱-质谱法 (GC-MS) 用于确定COO的化学成分.
- 使用DPPH自由基测定法测量了抗氧化活性.
- 抗病毒和抗菌特性通过HET-CAM,卵内抗病毒试验和光盘扩散方法进行评估.
主要成果:
- 在GC-MS分析中,COO中发现了40种不同的化合物.
- 和甲醇提取物表现出强烈的抗氧化活性,DPPH基抑制率分别为70%和63.3%.
- COO 提取物对四种致病病毒表现出显著的抑制作用,对大肠杆菌表现出显著的抑制区域.
结论:
- 克罗斯巴蒙东方油 (COO) 具有相当大的抗氧化和抗菌性质,归因于其多样化的生物活性成分.
- 这些发现凸显了COO作为开发天然治疗剂的有希望来源,具有针对病毒和细菌病原体的潜在应用.
- 建议进行进一步的研究,以隔离和表征COO中的特定生物活性化合物,用于药物开发.
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