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高压氧气治疗对热中风并发症多器官功能障碍的患者的影响:一项回顾性研究
Xiao-Xiao Ni1, Nian-Bo He2, Ye-Qun Guo1
1Department of Hyperbaric Oxygen Medicine and Rehabilitation, General Hospital of Southern Theater Command of PLA, Guangzhou, Guangdong, China.
Heliyon
|March 28, 2024
概括
高压氧气 (HBO) 治疗显著降低了人体热中风 (HS) 患者的死亡率和改善了器官功能. 这种治疗增强了神经和日常生活能力,为严重的HS提供了比传统护理更好的替代方案.
科学领域:
- 医学研究 医学研究
- 临床医学 临床医学
- 紧急医疗 紧急医疗
背景情况:
- 高压氧气 (HBO) 疗法在热中风 (HS) 的动物模型中显示出好处.
- 这项研究调查了HBO在患有HS和随后的多器官功能障碍的人类患者中的疗效.
研究的目的:
- 追溯分析HBO对人类热中风患者多器官功能障碍的影响.
- 为了比较接受HBO治疗的患者和接受常规治疗的患者之间的临床结果.
主要方法:
- 从单一医院的7年患者数据的回顾性分析.
- 将患者分为HBO和对照组进行分类.
- 测序器官衰竭评估 (SOFA),APACHE-II,神经学评分,器官功能标志物和修改的巴特尔指数 (MBI) 的比较.
主要成果:
- 在HBO组的死亡率为0%,而对照组的死亡率为8.49%.
- 接受HBO治疗显著改善了SOFA,APACHE-II和神经学分数.
- HBO治疗减轻了器官损伤,改善了肝脏和脏功能,并增强了日常生活能力 (MBI).
结论:
- 临床实践应考虑对严重的HS患者进行HBO治疗,这些患者有器官损伤和神经功能障碍.
- 结合的HBO疗法比HS的常规治疗更有效,改善器官功能和日常生活能力.
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