重症COVID-19患者的候群病:危险因素和对死亡率的影响
Sumeyye Kazancioglu1, Hurrem Bodur1, Ipek Mumcuoglu2
1Health Science University, Ankara Bilkent City Hospital, Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey.
Heliyon
|March 28, 2024
概括
淋病症显著增加了COVID-19患者的死亡率. 全腹腔营养 (TPN),发烧和低血压是COVID-19候选血症的关键预测因素,突出了早期识别和干预的必要性,以减少死亡率.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 流行病学 流行病学
背景情况:
- 在2019年新冠肺炎 (COVID-19) 疫情期间,重症监护室 (ICU) 的入院人数增加.
- 在COVID-19大流行之前,ICU中的候选病风险因素已经被确立.
研究的目的:
- 为了确定COVID-19患者候选血症的风险因素和预测因素.
- 在COVID-19的背景下分析与候选血症相关的患者特征和实验室数据.
- 确定候选血病对COVID-19患者死亡率的影响.
主要方法:
- 对患者数据的回顾性分析,包括特征和实验室结果.
- 三组的比较:患有COVID-19的候选性病,没有COVID-19的候选性病和患有COVID-19的非候选性病.
- 统计评估以确定相关因素和独立预测因素.
主要成果:
- 在COVID-19患者中,与候选血症相关的因素包括系统性炎症反应综合征 (SIRS) ≥2,固体恶性瘤,全腹腔营养 (TPN),中静脉导管 (CVC),低血压,发烧,尿素,氨酸转移酶 (ALT),D-二次体,公素,费里丁和三角中性粒细胞指数 (DNI).
- 在COVID-19中,候选血症的独立预测因素是TPN,低血压和发烧.
- 在患有COVID-19的候选血症患者中,医院死亡率的独立预测因素是尿素,乳酸和.
结论:
- кандидеми的存在显著增加了COVID-19患者的死亡率.
- TPN,发烧和低血压是COVID-19候选血症的强有力的预测因素.
- 识别COVID-19候选血症的特征对于预防和降低死亡率至关重要.
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