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胃空化和肌电活动测试在患有食道动的儿童:一个试点研究
Carlijn Mussies1, Gilles Duvoisin2,3, Angela Le4
1Department of Pediatric Gastroenterology and Nutrition, Emma Children's Hospital, Amsterdam UMC University of Amsterdam Amsterdam the Netherlands.
胃功能测试显示,80%的患有食道缩症 (EA) 的儿童有异常. 然而,这些胃功能异常与他们报告的生活质量没有相关性.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 胃肠道运动障碍 胃肠道运动障碍
- 遗传异常是一种先天性异常.
背景情况:
- 食道缩 (EA) 可以导致儿童的胃肠道问题和降低生活质量 (QOL).
- 评估胃功能对于了解这些并发症至关重要.
研究的目的:
- 评估EA儿童胃功能测试的可行性和临床实用性.
- 为了将胃功能测试结果与胃肠道症状和QOL相关联.
主要方法:
- 使用PedsQL胃肠道症状问卷 (PedsQL-GI) 进行症状和QOL评估.
- 用于C-胃排空的八酸呼吸试验 (C-GEBT) 用于胃排空.
- 使用表面电气胃学 (EGG) 来研究胃肌电活动.
主要成果:
- 在15名儿科患者中,80%的患者发现胃功能测试 (C-GEBT和/或EGG) 的异常.
- 在EGG上异常缓慢的波浪与异常胃排空的发病率较高有关.
- 在C-GEBT或EGG发现和PedsQL-GI得分之间没有观察到显著的相关性.
结论:
- C-GEBT和EGG是评估EA儿童胃功能的可行工具.
- 在这个群体中,胃功能异常的患病率很高.
- 尽管经常出现异常,但胃功能并没有显著影响报告的QOL或症状严重程度.
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