胰岛素抵抗/高胰岛素血症:一个重要的心血管风险因素,长期以来一直被低估
Serafino Fazio1, Valentina Mercurio1, Loredana Tibullo2
1Department of Internal Medicine, Federico II University Hospital, Naples, Italy.
Frontiers in cardiovascular medicine
|March 28, 2024
概括
胰岛素抵抗 (IR) 和高胰岛素血症 (Hyperins) 是重要的,但往往被忽视的心血管风险因素. 解决IR/Hyperins对于降低全球高心血管死亡率至关重要.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 代谢综合征是代谢综合征的一种.
背景情况:
- 尽管治疗方面取得了进展,但心血管疾病 (CVD) 的死亡率仍然很高.
- 已经确定的风险因素,如高血压和糖尿病是可以管理的,但胰岛素耐药性 (IR) 和高胰岛素血症 (Hyperins) 往往被忽视.
- 在全球范围内,IR/Hyperins的患病率正在增加,估计约有51%的人口受到影响.
研究的目的:
- 突出胰岛素抵抗 (IR) 和高胰岛素血症 (Hyperins) 作为关键的,低估的心血管风险因素.
- 鼓励科学界认识到和解决IR/Hyperins的心血管影响.
- 审查关于IR/Hyperins与心血管健康之间的关联的科学文献.
主要方法:
- 在PubMed,Scopus和Science Direct上进行全面的文献搜索.
- 关键词包括:胰岛素,胰岛素信号传导,胰岛素抵抗,高胰岛素血症,心血管风险因素,心血管系统,心血管疾病.
- 选择研究,重点研究IR/Hyperins与心血管系统之间的联系,包括查和治疗策略.
主要成果:
- 科学文献表明,被忽视的IR/Hyperins可以导致显著的负面心血管影响.
- 红外线/超蛋白与心血管系统密切相关,有助于心血管疾病.
- 在全球范围内,IR/Hyperins的流行率日益增加,这凸显了它们作为公共卫生问题的重要性.
结论:
- 红外线/高氨酸代表了一种显著且未得到充分解决的心血管风险.
- 及时查和治疗IR/Hyperins对于预防心血管疾病至关重要.
- 需要进一步的研究和临床关注IR/Hyperins,以减轻心血管死亡率.
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