老年患者的极度高等级的肉瘤,他们是外科手术的候选人吗? 在肉瘤转诊中心的经验
Daniel Escobar-Mendiola1, Lydia Mediavilla-Santos1, Rubén Pérez-Mañanes1,2
1Servicio de Cirugía Ortopédica Y Traumatología, Hospital General Universitario Gregorio Marañón, Calle Doctor Esquerdo, 46, 28007 Madrid, Spain.
Indian journal of surgical oncology
|March 28, 2024
概括
高度四肢瘤的老年和中年患者具有相似的生存结果. 对于这两组人群来说,手术是有效的,化疗在使用方面有所不同. 治疗应根据患者的健康状况进行个性化.
科学领域:
- 在瘤学瘤学.
- 老年医学 老年医学
- 手术瘤学手术瘤学
背景情况:
- 在老年人群中,癌症发病率正在上升.
- 关于老年人癌症管理的数据有限.
- 高度四肢瘤需要特殊的治疗考虑.
研究的目的:
- 为了比较老年人与中年患者的高度四肢肉瘤的管理和结果.
- 为了确定治疗策略和生存率的差异.
- 为老年癌症患者提供基于证据的护理信息.
主要方法:
- 在2011-2017年期间接受治疗的患者的回顾性队列研究.
- 两个组:老年人 (>=70岁) 和中年人 (30/50岁).
- 管理,化疗使用,整体存活率和无进展生存率的比较.
主要成果:
- 两组之间总体或无进展生存率没有显著差异.
- 在老年患者 (16.7%) 和年轻患者 (67.6%) 中,化疗的使用率明显较低.
- 其他原因导致的死亡在老年人群中更为常见.
结论:
- 在这两个年龄组中,手术是对瘤的首要治疗方法,产生类似的生存结果.
- 化疗的使用是治疗方案的主要差异化因素.
- 功能状况良好的老年患者应接受治愈性手术治疗;脆弱的患者需要以生活质量为重点的息治疗.
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