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Updated: Jun 29, 2025

Loss-of-Function Approach in the Embryonic Chick Retina by Using Tol2 Transposon-Mediated Transgenic Expression of Artificial microRNAs
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Loss-of-Function Approach in the Embryonic Chick Retina by Using Tol2 Transposon-Mediated Transgenic Expression of Artificial microRNAs

Published on: May 18, 2022

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转增强RNA表达功能性miRNA介导目标基因抑制和同时表达转基因

Ayşegül Yıldız1, Aida Hasani1, Tina Hempel1

  • 1TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University Mainz, Freiligrathstrasse 12, 55131 Mainz, Germany.

Molecular therapy. Nucleic acids
|March 28, 2024
PubMed
概括

这项研究表明,转增强RNA (taRNA) 可以提供治疗性蛋白质和功能性microRNA (miRNA) 来实现基因沉默. 塔RNA系统有效释放成熟的miRNA,使得持续的基因调节能够在不影响蛋白质表达的情况下进行.

关键词:
MT:交付策略的交付策略基因调节 基因调节 基因调节在 miRNA 递送过程中, miRNA 递送非病毒RNA载体的非病毒RNA载体.转增强RNA的转增强RNA是什么?通过复制的转复制.

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