相关实验视频

Updated: Aug 16, 2026

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
10:00

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes

Published on: March 24, 2015

13.4K

新的外周血液单核细胞mRNA签名用于IFN-β治疗响应预测多发性硬化症

Yang Xue1, Pengqi Yin2, Hongping Chen1

  • 1Department of Neurology, First Affiliated Hospital of Harbin Medical University, Harbin, China.

Autoimmunity
|March 28, 2024
PubMed
概括

这项研究开发了一种使用mRNA表达的新模型,以预测复发性复发性多发性硬化症 (RRMS) 患者对干扰素-β (IFN-β) 治疗的反应. 该模型识别了可能早期受益的患者,帮助治疗决策.

关键词:
通过IFN疗法进行治疗.多发性硬化症是多发性硬化症.药物反应能力 药物反应能力预测模型建设的预测模型.生存分析,生存分析.

更多相关视频

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

5.5K
Using Reference Reagents to Confirm Robustness of Cytokine Release Assays for the Prediction of Monoclonal Antibody Safety06:37

Using Reference Reagents to Confirm Robustness of Cytokine Release Assays for the Prediction of Monoclonal Antibody Safety

Published on: September 15, 2023

585

相关概念视频

Inhibitors of Viral Protein Synthesis01:30

Inhibitors of Viral Protein Synthesis

Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...