教育水平与癌症患者的生存率之间的关系:一个多中心队列研究
Xiao-Yue Liu1,2,3, Xi Zhang1,2,3, Guo-Tian Ruan1,2,3
1Department of Gastrointestinal Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Cancer medicine
|March 28, 2024
概括
在中国,高等教育水平与更好的癌症存活率有关. 通过患者生成的主观全球评估 (PG-SGA) 来评估营养状况的改善,进一步提高了癌症患者的预后.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 健康的社会经济决定因素
背景情况:
- 社会经济因素显著影响人口死亡率.
- 在中国,教育程度对癌症患者生存率的影响仍未得到充分探索.
研究的目的:
- 研究教育水平与癌症患者预后之间的关联.
- 确定影响这种关系的潜在调解者.
主要方法:
- 一项多中心队列研究,涉及18,251名在2013年5月至2018年12月期间诊断出癌症的癌症患者.
- 总生存率 (OS) 和全因死亡率是主要终点.
- 使用多因素校正的考克斯生存分析和后勤回归.
主要成果:
- 教育水平的提高与总体存活时间的显著延长相关 (HR=0.84,p<0.001).
- 学历水平独立地与更好的营养状况有关,如患者生成的主观全球评估 (PG-SGA) 分数较低所示.
- 诸如性别,年龄,TNM阶段和PG-SGA得分等因素影响了这种关联.
结论:
- 教育水平是癌症患者的重要,独立的预后因素.
- 通过PG-SGA测量营养状况的改善,可以增强高等教育的积极预后效应.
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