相关实验视频
Updated: May 9, 2026

08:35
Detecting Cortex Fragments During Bacterial Spore Germination
Published on: June 25, 2016
9.4K
不同的破墙方法在体外消化过程中对Ganoderma lucidum子粉末的营养释放的影响
Yaoyao Qi1, Shun Zhong1, Feng Pan2
1State Key Laboratory of Food Science and Resources, University of Nanchang, Nanchang, China.
Journal of the science of food and agriculture
|March 28, 2024
概括
打破Ganoderma lucidum子粉 (GLSP) 的硬细胞壁显著提高了其活性化合物的消化和吸收. 在低温下超细磨削 (UFG-L) 证明比在室温下机械磨削 (MM-R) 更有效.
科学领域:
- 生物技术是生物技术.
- 食品科学 食品科学 食品科学
- 药理学 药理学是指药理学的学科.
背景情况:
- 光胞粉 (GLSP) 具有强大的双壁结构,阻碍了人类的消化.
- 有效的细胞壁破坏对于最大限度地提高GLSP有益化合物的生物可用性至关重要.
研究的目的:
- 调查不同细胞壁破坏方法对GLSP的影响.
- 为了比较室温机械磨削 (MM-R) 和低温超细磨削 (UFG-L) 在增强GLSP消化和吸收方面的有效性.
主要方法:
- 用两种方法破坏了Ganoderma lucidum子粉 (GLSP) 细胞壁:在室温下机械磨粉 (MM-R) 和在低温下超细磨粉 (UFG-L).
- 实验室消化模型被用来评估多糖和三烯的释放和生物可访问性.
- 在处理后分析了子粉的形态和结构完整性.
主要成果:
- 与MM-R相比,低温超细研磨 (UFG-L) 更好地保持了GLSP的形态和结构完整性.
- 打破GLSP细胞壁显著增加了多糖和三烯的释放,与增加的特定表面积相关.
- 聚糖和三烯的生物可访问性在破碎的GLSP中显著更高,与MM-R相比,UFG-L通常产生更好的结果.
结论:
- 破坏GLSP细胞壁可以提高其活性成分的消化和吸收.
- 虽然UFG-L导致了比MM-R更低的特定表面积,但它导致了GLSP活性化合物的更高的生物可访问性.
- 这些发现表明UFG-L是加工GLSP更有效的方法,以提高营养素的生物可用性.
相关概念视频
Methods for Studying Drug Absorption: In vitro
In vitro experiments are crucial for understanding the transport and absorption of drugs through biological materials. These studies employ varied methods such as the diffusion cell method, the everted sac technique, and the everted ring technique.
The diffusion cell method uses a two-compartment cell, including a donor compartment with the drug solution, which simulates the environment where the drug is applied, and a receptor compartment with a buffer solution, which simulates the environment...
The diffusion cell method uses a two-compartment cell, including a donor compartment with the drug solution, which simulates the environment where the drug is applied, and a receptor compartment with a buffer solution, which simulates the environment...
In Vitro Drug Dissolution: Compendial Testing Models I
Compendial dissolution methods are standardized procedures defined by pharmacopeias to evaluate the rate at which a drug dissolves in a specific medium. These methods ensure batch-to-batch consistency, enable quality control, and support the prediction of drug bioavailability. They are critical for both immediate and modified-release drug products.The apparatuses used for dissolution testing differ in their design and mechanical function, but all aim to simulate the physiological environment of...
In Vitro Drug Dissolution: Alternative Methods
Alternative drug dissolution methods include the rotating bottle, intrinsic dissolution test, peristalsis, and the Franz diffusion cell method. The rotating bottle method involves meticulously rotating tightly capped controlled-release beads in a temperature-controlled bath. Periodic decanting of samples allows for residue assay, followed by refilling with fresh medium and testing at various pH levels to emulate the gastrointestinal tract conditions.In contrast, the intrinsic dissolution test...

