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相关概念视频

Lung Capacity01:47

Lung Capacity

The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.

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相关实验视频

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Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
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我们如何扩大肺捐赠者池?

Bronwyn J Levvey1, Gregory I Snell

  • 1Lung Transplant Service, Department of Respiratory Medicine, Alfred Hospital, Melbourne, and Monash University, Melbourne, Australia.

Current opinion in pulmonary medicine
|March 28, 2024
PubMed
概括
此摘要是机器生成的。

肺移植方面的创新正在扩大捐赠者群. 使用循环死亡和老年捐赠者的捐赠,以及活体肺输液,可以改善需要移植的患者的肺部可用性.

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相关实验视频

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科学领域:

  • 心血管和呼吸系统科学 心血管和呼吸系统科学
  • 移植科学 移植科学
  • 再生医学是一种再生医学.

背景情况:

  • 肺移植对于末期肺病至关重要,但由于供体肺的可用性而受到限制.
  • 临床实践和科学创新是克服这些局限性的关键.

研究的目的:

  • 审查最近在扩大移植供体肺池方面的进展.
  • 突出临床实践和科学发现的创新.

主要方法:

  • 对循环死亡 (DCD) 肺部捐赠者捐赠后的研究进行审查.
  • 对老年捐赠者 (>70岁) 的结果进行分析.
  • 评估利用肝炎C阳性供体肺部和ex-vivo肺 perfusion 的策略.

主要成果:

  • 成功的肺移植正在从所有类别的DCD捐赠者中增加.
  • 70岁以上的捐赠者正在产生比预期的更好的长期结果.
  • 肝炎C阳性供体肺部可以安全地与术后抗病毒药物一起使用;ex-vivo肺 perfusion 显示出供体管理的希望.

结论:

  • 捐赠者的肺比以前认为的更坚固.
  • 临床,科学和工程创新正在显著增加潜在的捐赠者肺池.
  • 这些进展为改善肺移植的可及性提供了希望.