用加尔坎祖马布作为偏头痛预防治疗的患者进行观察性回顾性研究:ORYGAM研究
Samuel Díaz Insa1, Ángel Guerrero2, Javier Viguera3
1Hospital Universitario y Politécnico de la Fe, Valencia, Spain.
Pain and therapy
|March 28, 2024
概括
加尔坎祖马布在真实世界偏头痛治疗中表现出有效性和高持久性. 大多数患者,通常是患有慢性偏头痛和先前治疗的患者,经历了每月偏头痛日数的显著减少.
科学领域:
- 神经学 神经学
- 临床药理学 临床药理学
- 现实世界的证据 现实世界的证据
背景情况:
- 在临床实践中关于加尔坎祖马布疗效的有限的现实世界数据.
- 需要了解西班牙galcanezumab的患者特征和治疗模式.
研究的目的:
- 描述在西班牙常规临床实践中用galcanezumab治疗的患者概况.
- 分析加尔坎祖马布治疗模式,持续性和有效性.
主要方法:
- 六家西班牙医院的回顾性图表审查.
- 对成人偏头痛患者开始服用加尔卡内祖马布的分析 (2019年11月至2021年9月).
- 卡普兰-梅尔治疗持久性的分析.
主要成果:
- 分析了314名患者;平均年龄为46.3岁,85%为女性,80.6%为慢性偏头痛.
- 伴随性疾病的高患病率 (72.9%) 和先前的治疗 (≥6对>60%).
- 12个月持久率为59.8%;平均减少9个偏头痛日/月.
结论:
- 加尔坎祖马布在现实世界偏头痛管理中显示出有效性和高持久性.
- 对于慢性偏头痛患者有效,具有广泛的先前治疗史.
- 支持galcanezumab在偏头痛临床实践中的作用.
相关概念视频
01:27Open Angle Glaucoma: Treatment
440
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
440
01:28Angle Closure Glaucoma: Treatment
485
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
485