一个无线的,可植入的生物电子系统,用于监测手术恢复后的膀功能
Jihye Kim1,2, Matthew I Bury3,4, Kyeongha Kwon5
1Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208.
概括
一种新的可植入装置在部分囊切除术后提供持续的实时膀监测,克服了传统尿动力学研究 (UDS) 的局限性,以改善患者康复评估.
科学领域:
- 生物医学工程 生物医学工程
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医疗器械 医疗器械
背景情况:
- 部分囊切除术的恢复需要使用尿动力学研究 (UDS) 监测下尿路功能.
- 无线数据系统提供间歇性数据,依赖于用户,并带有感染风险.
- 由于UDS的局限性,阻碍了对膀恢复的持续纵向评估.
研究的目的:
- 推出一种新的,可植入的平台,用于连续的,实时的膀监测.
- 评估平台作为传统UDS的替代品的有效性.
- 为了评估长期的术后膀恢复监测.
主要方法:
- 开发一个完全可以植入膀的平台,具有无线遥测.
- 包括一个无线,可生物吸收的张力计,用于机械张力测量.
- 在基板,动物和非人类灵长类动物部分囊切除模型中的验证.
主要成果:
- 该系统可重复测量动物的膀变化,在植入后的30天内进行实时测量.
- 观察到最少的异物反应.
- 非人类灵长类动物的研究显示,压力测量与UDS的一致性长达8周.
结论:
- 植入式平台为膀监测提供了传统UDS的可行替代方案.
- 持续的实时数据收集有助于更好地评估术后膀恢复.
- 该系统显示了部分囊切除术后增强患者护理的潜力.
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