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Updated: Jun 29, 2025

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皮里米丁维持线粒体的pyruvate氧化,以支持新的脂质生成

Umakant Sahu1,2, Elodie Villa1,2, Colleen R Reczek2,3

  • 1Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

Science (New York, N.Y.)
|March 28, 2024
PubMed
概括

尿素三酸 (UTP) 对于细胞能量产生至关重要,它支持酸循环和脂肪合成. 通过使维生素B1的利用,这种pyrimidine,而不是purin,为重要的代谢途径提供燃料.

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Pyruvate Oxidation01:15

Pyruvate Oxidation

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