在性外围神经刺激后,促进运动唤起的潜能
Zaman Wehab1, Michael W Lutz1, Emily P Bell1
1Department of Neurology, Duke University Medical Center, Durham, NC, USA.
概括
在大多数患者,包括患有骨髓病的患者中,使用外周神经刺激 (P-MEP) 技术,在经电刺激 (TES) 之前使用外周神经刺激,显著提高了运动唤起潜力 (MEP) 幅度.
科学领域:
- 神经科学是一个神经科学.
- 临床电生理学 临床电生理学
背景情况:
- 超电刺激 (TES) 用于引起运动唤起潜力 (MEP).
- 在TES之前的周围神经刺激可能会调节MEP幅度.
研究的目的:
- 为了研究后瘤MEP (p-MEP) 技术在增强MEP振幅方面的有效性.
主要方法:
- 传统的TES MEPs (c-MEP) 和具有上肢 (p-MEPUL) 或下肢 (p-MEPLL) 刺激的p-MEPs在26名患者中进行了比较.
- 分析了双边的手和脚MEP幅度.
- 对肌肉病和外围神经病患者进行了亚组分析.
主要成果:
- 在96%的患者中,p-MEPUL技术改善了MEP振幅,而p-MEPLL技术则改善了73%的患者.
- 在大多数肌肉群中观察到统计学上显著的MEP振幅增加.
- 在骨髓病组中也发现了类似的改善;神经病组对p-MEPLL的结果不尽相同.
结论:
- 在提高MEP振幅方面,p-MEP技术是有效的.
- 这种技术有望改善手术期间的MEP,特别是在骨髓病患者中.
- 在患有外围神经病变的患者中,p-MEP的有效性可能是有限的.
相关概念视频
Muscle Stimulation Frequency
2.2K
The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
2.2K
Motor Unit Stimulation
1.5K
When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
1.5K


