在肺癌查人口中,在低剂量CT上对骨质疏松症的视觉评分
Yeqing Zhu1, Rowena Yip1, Artit C Jirapatnakul1
1Department of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai, One Gustave Levy L. Place, New York, NY 10029, United States of America.
Clinical imaging
|March 28, 2024
概括
这项研究开发了一种用于骨质疏松症的视觉评分系统,使用来自肺癌查的低剂量CT扫描. 该方法是可行的和准确的,用于识别风险患者的骨质疏松症.
科学领域:
- 放射学 放射学是一门学科.
- 骨质疏松症研究 骨质疏松症研究
- 公共卫生查 公共卫生查
背景情况:
- 骨质疏松症与肺癌具有共同的风险因素 (年龄,吸烟史).
- 用于肺癌查的低剂量计算机断层扫描 (LDCT) 越来越常见.
- 在无症状人群中需要有效的骨质疏松症查方法.
研究的目的:
- 开发和验证用于骨质疏松症检测的视觉评分系统.
- 评估使用肺癌查中的LDCT扫描用于骨质疏松症评估的可行性.
- 将视觉评分与自动测量进行比较,并评估读者之间的共识.
主要方法:
- 在肺癌查计划中对1000名参与者的回顾性审查.
- 应用特定的窗口宽度 (230) 和水平 (80) 设置用于视觉评估.
- 视觉骨质疏松症得分与自动软件测量结果的比较.
- 在六位具有不同经验水平的放射科医生之间进行了读者间协议评估.
主要成果:
- 在77.4%的参与者中,自动骨质疏松症测量成功.
- 骨质疏松症在17.8%的被评估参与者中被发现.
- 在自动测量和视觉骨质疏松症得分之间发现了显著的相关性 (p < 0.0001).
- 在骨质疏松症分类方面,获得了大量至优异的读者间一致性 (Fleiss κ = 0.91).
结论:
- 使用特定LDCT设置的简单视觉评分系统可以有效地识别骨质疏松症.
- 这种方法在肺癌查期间对机会性骨质疏松症查是可行的和有用的.
- 将骨质疏松症查纳入肺癌查计划可以改善早期检测和管理.
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