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Updated: Jun 29, 2025

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空心硫酸盐组的牺牲模板合成功能化微孔有机网络,以从牛奶和蜂蜜样本中有效地提取硫胺抗生素的固体相提取

Shuo-Wen Gao¹, Li-Hua Chen², Yuan-Yuan Cui¹

¹School of Pharmaceutical Sciences & Institute of Materia Medica, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China.

Journal of chromatography. A

|March 28, 2024

概括

一种新的空心微孔有机网络 (H-MON-SO3H-2) 从复杂的样本中有效地提取硫胺. 这种功能化的材料具有很高的灵敏度和可重复使用性,用于环境和食品分析.

科学领域:

材料科学材料科学材料科学
分析化学分析化学
环境科学环境科学

背景情况:

微孔有机网络 (MON) 具有结合性和疏水性质,限制了它们在对极性或离子分析物的样品预处理中的使用.
开发有效的预处理方法对于分析水,牛奶和蜂蜜等复杂矩阵中的微量污染物至关重要.

研究的目的:

为了合成一种新的,均的空心形状的硫酸盐组,功能化了MON (H-MON-SO3H-2).
评估H-MON-SO3H-2在从环境和食品样本中固体相提取 (SPE) 硫胺 (SAs) 的效率.
通过高性能液态染色学 (HPLC) 在微量分析中证明H-MON-SO3H-2的潜力.

主要方法:

牺牲模板方法用于合成H-MON-SO3H-2.
固相提取 (SPE) 技术使用合成的H-MON-SO3H-2.
高性能液体染色学 (HPLC) 用于硫胺分析.

主要成果:

H-MON-SO3H-2具有较大的表面积,可穿透的结构和良好的稳定性.
该材料对SA具有广泛的线性范围 (0.150-1000μg L-1) 的SA表现出色的SPE性能.
实现了低检测极限 (0.045-0.188μg L-1),高吸附能力 (250.4-545.0 mg g-1),以及良好的重复使用性 (>80个周期).
在的环境水,牛奶和蜂蜜样本中成功应用,回收率高 (86.1-104.3%).

结论:

合成的H-MON-SO3H-2对复杂矩阵中微量硫胺的敏感SPE非常有效.
空洞MON显示出对先进的样品预处理应用的显著前景.
这种方法增强了环境和食品安全监测中硫胺的分析.

关键词:

在HPLC中使用HPLC.空洞的微孔有机网络.样品预处理样品预处理固相提取固相提取的方法硫胺是什么硫胺是什么

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