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Updated: Jun 29, 2025

Facile Preparation of 4-Substituted Quinazoline Derivatives
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作为人类尿酸载体1抑制剂的林衍生型胺化合物具有强大的尿酸降低活性

Shengnan Li1, Hui Liao2, Lijun Luo1

  • 1Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, PR China.

European journal of medicinal chemistry
|March 28, 2024
PubMed
概括

新的林衍生的林形式胺有效抑制人体尿酸转运体1 (URAT1). 这些化合物显示出通过降低尿酸水平来治疗高尿血和痛风的前景.

关键词:
它具有抗炎活性,具有抗炎活性.药物适应性 药物适应性 药物适应性 药物适应性超性血症 (hyperuricemia) 是一种疾病,奎诺林形式胺化物乌拉特1是URAC1的产品之一.

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