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环境因素是否会增加暴露于多环芳 (PAHs) 的鱼类的氧化反应?

Tatiana Recabarren-Villalón¹, Ana C Ronda², Lautaro Girones³

¹Instituto Argentino de Oceanografía IADO - CONICET/UNS, Camino La Carrindanga km 7.5, 8000, Bahía Blanca, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas CONICET, Argentina; Universidad San Sebastián USS, Lientur, 1457, Concepción, Chile.

|March 28, 2024

概括

鱼类中的多环芳 (PAH) 与氧化应激生物标志物有关. 像pH和温度这样的环境因素会影响PAH的毒性,影响鱼类健康和生态毒理学.

科学领域:

环境毒理学环境毒理学
生态毒理学生态毒理学
生物标志物研究的研究.

背景情况:

多环芳 (PAH) 是一种环境污染物.
氧化应激生物标志物 (脂质过氧化,谷,谷S转移酶) 是细胞损伤的指标.
河口环境容易受到PAH污染.

研究的目的:

研究PAHs,氧化应激生物标志物和Ramnogaster arcuata中的环境因素之间的关系.
为了确定PAH暴露和河口鱼类中毒性的潜在生物标志物.
评估环境参数对PAH毒性的影响.

主要方法:

在鱼类肌肉组织中PAH水平的现场评估.
在鱼组织中测量脂质过氧化,谷氨和谷氨S转移酶活性.
对PAH度,生物标志物水平和环境因素 (温度,pH,盐度) 之间的相关性分析.

主要成果:

在R. arcuata中,PAH水平在0.7至293.4 ng g-1湿重之间.
脂质过氧化和肌肉谷氨与总和特定PAHs有正相关性.
肝脏谷氨酸S转移酶与4环PAHs负相关.
环境因素,特别是pH和温度,与PAH水平和生物标志物反应有显著的相关性.
pH与三环PAH和几个生物标志物有负相关.
温度与2环PAHs有负相关性,与肌肉谷氨有正相关性.

结论:

脂质过氧化和肌肉谷氨是复杂PAH混合物的潜在生物标志物.
肝脏氨酸S转移酶可以作为4环PAHs的生物标志物.
物理化学参数影响河口鱼的PAH毒性.
了解这些相互作用对于预测在变化的环境条件下生态毒理学影响至关重要,例如海洋变暖和酸化.

关键词:

生物标志物生物标志物环境因素环境因素鱼类鱼类鱼类鱼类氧化应激是一种氧化应激.这些PAHs是PAH.污染物污染物污染物

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