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Updated: Jul 16, 2026

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结核菌病毒S调节器的晶体结构揭示了其与化合物SMARt751的相互作用

Camille Grosse1, Maud Sigoillot2, Véronique Megalizzi2

  • 1Unit of Microbiology, Bioorganic and Macromolecular Chemistry, Department of Research in Drug Development, Faculty of Pharmacy, Université Libre de Bruxelles, Belgium; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Center for Infection and Immunity of Lille, F-59000 Lille, France.

Journal of structural biology
|March 28, 2024
PubMed
概括

研究人员阐明了VirS的晶体结构,VirS是结核病治疗中以胺胺激活的调节剂. 这一发现揭示了SMARt751如何与Virus结合,为新的结核病疗法铺平了道路.

关键词:
阿尔法折叠模型模型在 AraC 调节器上.埃塞俄比亚的想法蛋白联体复合体 蛋白联体复合体在X射线晶体学.

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