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Updated: Jun 29, 2025

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
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TGF-β1驱动着因特林依赖的细胞迁移和纤维性疾病中的微血管不稳定

Amanda S Pellowe1, Michelle J Wu1, Tae-Yun Kang1

  • 1Department of Biomedical Engineering, Yale University, New Haven, Connecticut.

The American journal of pathology
|March 28, 2024
PubMed
概括

皮细胞 (PCs) 在纤维性疾病中从血管迁移,由转化生长因子β1 (TGF-β1) 和整体素驱动. 这种迁移会破坏微血管的稳定,表明早期的组织纤维化.

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