为研究艾滋病毒耐药性流行率或发病率制定报告项目检查清单:混合方法研究
Cristian Garcia1,2, Anne Holbrook3,4,5, Pascal Djiadeu6,7
1Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada cristian.garcia@mail.utoronto.ca.
BMJ open
|March 28, 2024
概括
本研究详细介绍了制定报告指南的方法,以改善艾滋病毒耐药性监测. 该指南提高了HIV耐药性流行率和发病率研究的数据质量和可解释性.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 由于数据报告不一致,HIV耐药性监测受到阻碍.
- 之前的工作为艾滋病毒耐药性流行率和发病率研究制定了报告指南.
研究的目的:
- 描述用于开发HIV耐药性研究报告指南的混合方法方法.
- 为此类研究创建一个全面的检查清单,包括必要的报告项目.
主要方法:
- 采用了一种连续解释混合方法设计.
- 定量阶段:横截面电子调查 (n=51) 以确定基本报告项目.
- 定性阶段:聚焦小组讨论 (n=9) 精细化和证明报告项目.
主要成果:
- 确定了38个潜在的报告项目,以描述参与者,提高结果的解释性,并澄清抗性测试方法.
- 综合项目到报告检查清单中.
- 定性见解为指导组件提供了合理的依据.
结论:
- 为艾滋病毒耐药性发病率/流行率研究创建了一个报告项目列表,并提供了理由.
- 混合方法促进了项目列表和定性见解的综合开发.
- 调查结果为改善监督的公布报告指南提供了信息.
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