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相关概念视频

Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

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An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
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MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

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Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.
Matrix-assisted laser desorption ionization (MALDI) is a commonly...
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相关实验视频

Updated: Jun 29, 2025

Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles
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Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles

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新抗原鉴定:技术进步和挑战

Ting Pu1, Allyson Peddle1, Jingjing Zhu2

  • 1Digestive Oncology Unit, KULeuven, Leuven, Belgium.

Methods in cell biology
|March 28, 2024
PubMed
概括

新抗原,独特的瘤点,对于像疫苗一样的癌症免疫疗法至关重要. 需要改进的预测工具,但对免疫新抗原的验证数据仍然是一个挑战.

科学领域:

  • 在瘤学瘤学.
  • 免疫学 免疫学 免疫学
  • 生物信息学是一种生物信息学.
关键词:
计算工具是一种计算工具.哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈免疫治疗是一种免疫疗法.新抗原是一种新抗原.新抗原预测的预测身体突变的体质突变在TCR中,可以使用TCR.

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背景情况:

  • 新抗原是来自遗传和非基因组变化的瘤特异性标.
  • 它们对于开发个性化癌症疫苗和采用细胞疗法至关重要.
  • 技术的进步促进了免疫新抗原的识别.

结论:

  • 新抗原的预测和验证对于推进癌症免疫疗法至关重要.
  • 计算工具的进一步开发受到验证免疫新抗原数据集的缺乏所阻碍.
  • 利用新抗原在对抗癌症的斗争中具有显著的前景.