综合老年医学评估中基于性别的差异,在患有非膜性心房动的老年住院患者中
Giuseppe Armentaro1, Daniele Pastori2, Alberto Castagna3
1Department of Medical and Surgical Sciences, University Magna Græcia of Catanzaro, 88100 Catanzaro, Italy.
European journal of internal medicine
|March 28, 2024
概括
心房动 (AF) 与老年患者的认知衰退和抑郁症有关. 女性性别和认知障碍增加了风险,而功能改善和某些疗法提供了保护.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 神经学 神经学
背景情况:
- 心房动 (AF) 是最常见的超心室心律失常,影响全球人口的1-3%.
- 新兴证据将AF与认知障碍 (CoI),痴呆症,抑郁症和功能限制联系在一起.
研究的目的:
- 为了确定COI,抑郁症和功能限制的患病率,在接受直接口服抗凝剂 (DOACs) 的老年住院患者中,非膜性AF (NVAF) 的老年患者.
- 为了确定增加或保护这种队列中CoI或功能限制的风险的因素.
主要方法:
- 分析了一组1004名老年患者 (平均年龄84±7.1岁),在DOAC上患有NVAF.
- 人口统计,临床变量和分数 (CHA2DS2-VASc,HAS-BLED) 在性别之间进行了比较.
- 评估了心血管梗塞,抑郁症和功能限制的患病率,并进行了风险因素分析.
主要成果:
- 在接受DOAC治疗的老年住院AF患者中,认知障碍和残疾非常普遍.
- 女性的性别与三倍增加的coI风险有关;功能性改善将这种风险降低了15%.
- 心血管梗塞和抑郁症状增加了功能障碍的风险 (分别是2倍和28%),抗高血压和抗糖尿病疗法降低了这种风险.
结论:
- 在接受DOAC治疗的老年NVAF患者中,常见的是coI和功能限制.
- 女性的性别是COI的重要危险因素,而功能性改善是保护性的.
- 通过适当的治疗来管理COI,抑郁症和并发症,对于改善这一群体的功能结果至关重要.
更多相关视频
04:05Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
Published on: June 30, 2023
1.8K
08:10Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
1.7K
相关概念视频
01:23Assessment of the Cardiovascular System I: Subjective Data
323
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
323
01:26Imbalances in Cardiac Output
1.4K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.4K